IL-2 Production Response Downstream of TCR Activation Can Predict Quantitative Network Signal Combinations
نویسندگان
چکیده
منابع مشابه
Quantitative network signal combinations downstream of TCR activation can predict IL-2 production response.
Proximal signaling events activated by TCR-peptide/MHC (TCR-pMHC) binding have been the focus of intense ongoing study, but understanding how the consequent downstream signaling networks integrate to govern ultimate avidity-appropriate TCR-pMHC T cell responses remains a crucial next challenge. We hypothesized that a quantitative combination of key downstream network signals across multiple pat...
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